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HS Code |
803596 |
| Cas Number | 359-50-6 |
| Molecular Formula | C3H4F4O |
| Molecular Weight | 136.06 g/mol |
| Synonyms | TFP, Tetrafluoropropanol |
| Appearance | Colorless liquid |
| Boiling Point | 87-88 °C |
| Melting Point | -41 °C |
| Density | 1.432 g/cm³ at 25 °C |
| Refractive Index | 1.299 at 20 °C |
| Flash Point | 68 °C (closed cup) |
| Solubility In Water | Miscible |
| Vapor Pressure | 38 mmHg at 25 °C |
As an accredited 2,2,3,3-Tetrafluoro-1-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
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Purity 99.5%: 2,2,3,3-Tetrafluoro-1-Propanol with purity 99.5% is used in pharmaceutical intermediate synthesis, where high product yield and reduced by-product formation are achieved. Boiling point 85°C: 2,2,3,3-Tetrafluoro-1-Propanol with a boiling point of 85°C is used in specialty solvent applications, where controlled distillation and low residue enable high process efficiency. Molecular weight 130.04 g/mol: 2,2,3,3-Tetrafluoro-1-Propanol at a molecular weight of 130.04 g/mol is used in fine chemical manufacturing, where precise molecular formulation ensures batch consistency. Stability temperature up to 60°C: 2,2,3,3-Tetrafluoro-1-Propanol with stability temperature up to 60°C is used in polymer modification processes, where thermal integrity preserves reactivity. Viscosity 1.2 cP: 2,2,3,3-Tetrafluoro-1-Propanol of viscosity 1.2 cP is used in fluorinated coating formulations, where optimal flow and uniform film formation are obtained. Water content <0.05%: 2,2,3,3-Tetrafluoro-1-Propanol with water content below 0.05% is used in electronic material production, where low moisture guarantees electrical reliability. Density 1.432 g/cm³: 2,2,3,3-Tetrafluoro-1-Propanol with density 1.432 g/cm³ is used in high-performance fluid blends, where precise mass balance and fluid compatibility are maintained. |
| Packing | A 100 mL amber glass bottle with a tight-sealed cap, labeled as 2,2,3,3-Tetrafluoro-1-Propanol, for laboratory use. |
| Container Loading (20′ FCL) | 20′ FCL can load approximately 14MT of 2,2,3,3-Tetrafluoro-1-Propanol, typically packed in 250kg steel drums or IBCs. |
| Shipping | 2,2,3,3-Tetrafluoro-1-Propanol should be shipped in tightly sealed containers, protected from moisture and incompatible materials. Transport in compliance with applicable local, national, and international regulations, such as DOT and IATA. Handle as a hazardous material, typically under UN identification, and with appropriate labeling, including hazard warnings for toxic or corrosive substances. |
| Storage | **2,2,3,3-Tetrafluoro-1-propanol** should be stored in a tightly closed, clearly labeled container in a cool, dry, well-ventilated area away from heat, flames, and incompatible substances such as strong oxidizers and acids. Use secondary containment to prevent leaks or spills. Protect from moisture and store under an inert atmosphere if necessary. Follow all appropriate chemical hygiene and safety protocols. |
| Shelf Life | 2,2,3,3-Tetrafluoro-1-Propanol typically has a shelf life of 2 years when stored in a cool, dry, tightly sealed container. |
Competitive 2,2,3,3-Tetrafluoro-1-Propanol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615651039172 or mail to sales9@bouling-chem.com.
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Over the last decade, we have continually observed transforming priorities across chemical manufacturing—especially among fluorinated intermediates. From experience, we know 2,2,3,3-Tetrafluoro-1-Propanol stands out as a unique building block in both laboratory and industrial scenarios. Chemists searching for advanced solvents, specialty intermediates, or performance-enhancing additives increasingly focus on this molecule due to its molecular structure and consistent reactivity.
Our production emphasizes the difference genuine tetrafluoro compounds ensure. Compared to other propanols, the four fluorine atoms on the backbone provide hydrolytic stability and volatility profiles distinctly superior to non-fluorinated analogs. This material’s clear, colorless liquid form and characteristic odor fit right into standardized lab settings. Yet, it is not only about appearances—chemical resistance is the big story.
For developers requiring low boiling points or robust hydrogen bonding in organic synthesis, few candidates offer the same physical attributes. We have seen R&D teams, at both pilot and commercial scales, gravitate toward this compound for reactions where selectivity and reduced side-products are not negotiable. Its polar hydroxyl functional group allows for direct participation in coupling reactions, and the fluorinated backbone minimizes unwanted cross-reactions.
We manufacture 2,2,3,3-Tetrafluoro-1-Propanol under tightly controlled conditions, using high-purity feedstocks and custom fine-tuned distillation. Consistency and traceability drive every batch, and impurity levels sit well below the needs of most pharma or electronic applications. Our standard output model runs a purity of at least 99%. This purity figure springs from both rigorous column separation and advanced analytical control.
In practice, downstream users require absolute clarity—GC-MS and NMR data consistently confirm the absence of halogenated byproducts. We sell it as a neat liquid in high-density fluoropolymer-lined containers, and nothing leaves our warehouse without passing internal audit. Direct experience in scaling batch volumes lets us accommodate novel projects: whether a few liters or multi-ton lots, our reactors run to the actual specification, not generic merchant standards.
Once out of the drum and into the process line, this product tells its own story. Its boiling point sits below most non-fluorinated propanols, aiding applications where controlled evaporation and quick solvent removal matter. The hydrogen on the alcohol group maintains a lively nucleophilicity, managing esterification and etherification with fewer complications than densely fluorinated alcohols on higher carbon numbers.
In laboratory synthesis, 2,2,3,3-Tetrafluoro-1-Propanol complements a growing toolbox of designer solvents. Its relatively low viscosity and high vapor pressure mean our clients rarely buckle under slow reaction kinetics or residual solvent headaches. The product’s chemical stability also protects downstream processes from over-oxidation or chain scission, even under elevated temperatures or in the presence of transition metal catalysts.
Most of our customers see measurable results by swapping out traditional alcohols with this derivative in pharmaceutical development, electronic chemical formulations, surface treatment, and specialty resins. In the life sciences sector, synthesis teams take advantage of this compound’s electron-withdrawing power. Nucleophilic substitution reactions, especially those forming carbon-oxygen frameworks, report increased yields under milder conditions. We regularly receive feedback on target molecule purity and improved reproducibility, especially from teams working under time and budget constraints.
In semiconductor processing, users demand chemicals that will not degrade sensitive thin films or trigger outgassing during photolithography. The tetrafluoro structure minimises problematic ash residue and suppresses microcontamination. Our collaboration with microfabrication engineers has taught us to focus every step of production on cleanliness, and analysis of every lot includes particle count and trace element scans.
We also see robust uptake among developers formulating fluorinated acrylics and polymer blends. Thanks to its volatility and controlled reactivity, this material inserts fluoroalkyl groups without triggering runaway polymerization or unwanted side reactions. Final product clarity and flexibility rise when our propanol is used as a chain transfer agent, especially in UV-curable composites and specialty copolymer systems.
We often help customers compare 2,2,3,3-Tetrafluoro-1-Propanol against more conventional alcohols or fluorinated intermediates. The conversation usually centers on reactivity, boiling range, and environmental behavior. Many propanol-based reagents lack the required electron deficiency to drive high-fidelity coupling reactions. Non-fluorinated analogs display greater hydrogen bond donor-acceptor strength, but suffer in selectivity, especially under base- or acid-catalyzed conditions.
Moving to the fluorinated alcohol class, chain length and substitution pattern control volatility, solubility, and metabolic fate. Some clients initially choose 2,2,2-Trifluoroethanol, but later report issues with excessive volatility and higher susceptibility to oxidation. By contrast, the four-fluorine configuration on our propanol backbone strikes a balance: quick evaporation, moderate solvent power, and diminished toxicity relative to longer-chain perfluoroalcohols. Our analytical team has run comparative tests alongside 2,2,2-Trifluoroethanol and 1,1,1,3,3,3-Hexafluoro-2-propanol. Each time, the target selectivity and byproduct profile favor our tetrafluoro-propanol for fine chemical synthesis and microelectronic development.
Many solvent buyers worry about environmental impact. While all fluorinated chemicals deserve careful stewardship, our process permits maximum recovery and reuse, minimizing losses to air and water. Our internal systems trap vented organofluorines and recycle them into subsequent reaction batches. The short-chain nature of this material results in faster, more predictable breakdown under UV and other advanced treatment processes, a feature not shared by persistent, long-chain perfluoroalkyl substances (PFAS).
Our experience shows safety must be woven into every stage, not left to the last. We train our technical and logistics teams directly, focusing on the best way to decant and transfer this alcohol in both bench-top and automated setups. Because its volatility raises potential inhalation risk, our facilities run contained feed systems and install real-time vapor monitors. Clients routinely request guidance on waste handling and long-term storage, and we openly share practices that have kept our record clean.
On the regulatory side, the way authorities scrutinize fluorinated chemicals is shifting. We do not cut corners—our compliance approach always holds up to third-party testing. Every product lot ships with analytical trace data, and chains of custody stop every shortcut before it can emerge. Audit logs go back years, showing not just the chemical itself but also the stabilizers and cleaning agents involved across the cycle.
We have invested in closed-loop discharge and vapor recovery systems, not as a branding exercise but because we want to keep process economics and environmental performance aligned. Emissions from 2,2,3,3-Tetrafluoro-1-Propanol never leave unchecked; cross-department teams regularly test effluents for trace fluorine and organics. Our collaborations with academic and private partners keep us ahead of both regulatory shifts and practical barriers to sustainable use.
We regularly donate small-lot samples to green chemistry programs, supporting research that targets safer, lower-waste syntheses. Researchers at several leading universities have used our material in pilot-scale hydrogen exchange studies and late-stage functionalization of pharmaceutical scaffolds. Their feedback motivates us to refine purity, catalyst compatibility, and packaging.
Downstream recyclability also rises in importance. In our experience, standard distillation readily purifies spent 2,2,3,3-Tetrafluoro-1-Propanol, and our customers now return solvent drums for centralized cleaning and filtration. Over three years, this loop has cut usage rates for several buyers by over 30% without any reduction in yield or process robustness.
For electronic and polymer applications, we focus on lowering emissions at the user site. By adjusting volatility and stabilizer content based on individualized feedback, we help end-users tune their mixing and curing steps. This reduces process variability and aligns with both supply chain targets and environmental safety.
We do not just dispatch shipments—we partner at the formulation stage. Commercial users sometimes encounter sluggish kinetics or unexpected side reactions when transitioning from bench to plant scale. In such cases, our technical team participates in trial reactions, diagnostic analysis, and process optimization. We have learned firsthand that minor impurities or process interruptions can ripple through a batch. By maintaining a direct feedback loop, we avoid guesswork and share time-tested adjustments.
Our own R&D group tests process variations with different catalysts, solvents, and temperatures. These comparative studies often yield actionable improvements—not just for us, but for our clients who rely on clear answers under tight delivery schedules. For several adhesive resin clients, replacing legacy alcohols with 2,2,3,3-Tetrafluoro-1-Propanol allowed for faster cure rates and lower outgassing, directly reflecting our earlier in-house studies. Every technical report we prepare aims to go beyond “fit for purpose”—extending to solvent recycling, wastewater cleanup, and safe vapor capture.
On-site troubleshooting forms a big part of our connection with end-users. Some production lines need extra anti-static protection or vapor scrubbing; others push for additional product documentation or trace impurity modeling before committing to scale-up. We adapt by maintaining low sample minimums, rapid turnaround on purity certificates, and flexibility in setup. Over the years, this responsiveness has formed genuine, trust-based working relationships with buyers and line engineers.
Market needs shift faster today, sometimes overnight. We have built agility into our planning—from rapid production scale-up to expedited sample analysis. As pressures mount for lower emissions or stricter byproduct thresholds, we revise both our synthetic pathways and waste handling protocols. The shift toward green manufacturing is more than trend-speak. For instance, as industry OEMs raise flags over PFAS content, our short-chain, low-residue 2,2,3,3-Tetrafluoro-1-Propanol remains the better fit compared to heavy perfluoroalkyl alternatives that authorities now phase out.
In our experience, open communication with regulatory agencies, customers, and research partners opens the way for more practical, workable standards. We often review new workplace exposure limits, update SDS sheets, and adapt storage guidelines accordingly. Clients new to fluorinated intermediates can tap our compliance team for risk analysis, waste minimization, and employee training resources built from direct shop-floor experience.
We track evolving end-of-life treatment technologies closely. UV oxidation, advanced adsorption, and catalytic combustion remain top contenders for post-use breakdown. We offer tested guidelines to all of our clients wanting to meet best practices for their own downstream effluents. Increasingly, companies want server-to-server data on emissions tracking, not paper logs; we meet this need with digital chain-of-custody tracing for every 2,2,3,3-Tetrafluoro-1-Propanol batch.
Every order that leaves our site reflects living lessons—what works, what fails, and what can make the next batch better. Nobody meets better process performance by standing still. Direct engagement with R&D labs and production users motivates continuous improvement, whether in purity, delivery schedules, container design, or document transparency.
We recognize the stakes remain high. Researchers and formulators rely on us for results—fewer side reactions, higher yields, and safer work environments. By focusing on both the chemistry and the practical, day-to-day needs of users, we carry forward a shared interest in innovation and stewardship. We believe that as industry, academia, and regulators pull together, the full potential of 2,2,3,3-Tetrafluoro-1-Propanol will emerge for cleaner, more productive processes in chemicals and beyond.
Through years of firsthand handling, testing, and listening, we have seen 2,2,3,3-Tetrafluoro-1-Propanol add tangible value in synthesis, processing, and product performance. Its unique structural features, tight specification control, and proven environmental stewardship shape a future safely anchored in responsible chemistry. The journey has shown us that the right material, made the right way, keeps projects on track.
